The results of rectal cancer were treated with preoperative short- course radiation combined laparoscopic total mesorectal excision

Downloads

Download data is not yet available.
PDF (Tiếng Việt)     49    18

Abstract

Objective: To assess the results of laparoscopic surgery treatment for mild and low rectal cancer, stage II, III with preoperative short-course radiation.

Patients and method: 59 patients with resectable mild and low rectal cancer were treated with short- course radiation combined laparoscopic total mesorectal excision in 108 Military Central Hospital, from 08/2015 to 07/2017. The patient’s data were recorded: patient’s and tumor’s characteristics, acute and late toxicity of the preoperative radiotherapy, response after preoperative radiotherapy and result of the operation.

Result: Mean age was 58.4 ± 9.93 ( 34-81 years ). Low rectal cancer was 49.2% and mild rectal cancer was 50.8%. Diagnosis was base on MRI 3.0 tesla with stage II: 10.2% and stage III: 89.8%. Pathology staging with stage I: 20.3%, stage II: 54.2%, stage III: 25.5. 11.9% patients have Acute toxicity of the preoperative radiotherapy with grade 1 and 8.5% have Late toxicity of the preoperative radiotherapy grade 2.3. Mean operative time was 142 ± 35 Conversion rate to open surgery was 5.1%, intraoperative complication was 5.1%. Early complication was 28.9%. Mean postoperative time was 10.7±4,6 days. 77.9% patients have response from grade 1 to grade 4 after preoperative radiotherapy.

Conclusion: laparoscopic total mesorectal excision is favorable for mild, low rectal cancer stage II,III with preoperative short-course radiation.

References

Nguyễn Hoàng Bắc, Nguyễn Trung Tín, Đỗ Minh Đại, Từ Đắc Hiền, Lê Quan Anh Tuấn (2006). “Cắt toàn bộ mạc treo trực tràng bằng phẫu thuật nội soi trong ung thư trực tràng thấp”. Y học Việt Nam, 319, tr. 131-138.

Bill J. Heald (2010).“Technical Notes on TME for Rectal cancer”. Atlas of procedures in surgical oncology. P. 187-194.

Brown G et al (2003). “Morphological predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison”. Radiology 227(20): 371-377

B. Glimelins, E. Tiret et al (2013). “Rectal cancer : ESMO Clinical Practice Guedelines for Diagnosis, treatment and Follow-up”. Annals of Oncology 24 (supplement 6): vi 81-vi88.

Delgado S, Momblan et al (2004). “Laparoscopic – assisted approach in rectal cancer patients : lessions from > 200 patients” SurgEndosc. 18: 1457-1462.

K.C.M.J. Pecters, C.T.H. Van de Velde at al (2005). “Late side effects of short-coure preoperative radiotherapy combined with total mesorectal excision for rectal cancer: Increased bowel dysfunction in irradiated patients- A Dutch colorectal cancer group study”. J. clinOncol 23: 6199-6206

D.P. Korkolis, G.D. Plataniotis (2006) Short-term preoperative radiotherapy is a safe approach for treatment of locally advanced rectal cancer. Colonrectal Dis 21: 1-6.

Marisa D. Santos, Cristina Silva et al ( 2014). “Prognostic Value of Mandard and Dworak Tumor Regression Grading in Rectal Cancer: Study of a SingleTertiaryCenter”ISRN Surgery Volume 2014, Article ID 310542, 8 pages.

Marijnen, C.A et al ( 2002 ). “ Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of muilticenter randomized trial”. J. Clin. Oncol. 20: 817-825.

Morino et al (2003). “Laparoscopic total mesorectal excision: a consecutive series of 100 patients”. Ann Surg. 237: 335-342

Rew, D.A., et al. (1991), “Proliferation irradiation in operable cancer of the rectum”, report of the Toronto trial –Can. J. surg. 20, pp. 335-338.

Published 27-08-2018
Fulltext
PDF (Tiếng Việt)     49    18
Language
Issue No. 50 (2018)
Section Original article
DOI
Keywords Phẫu thuật nội soi, ung thư trực tràng, xạ trị ngắn ngày Laparoscpic surgery, rectal cancer, short-course radiation

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright (c) 2025 Journal of Clinical Medicine Hue Central Hospital

Tuan, N. A., Hoai, N. T., Duong, T. T., Du, N. V., & Hiep, P. V. (2018). The results of rectal cancer were treated with preoperative short- course radiation combined laparoscopic total mesorectal excision. Journal of Clinical Medicine Hue Central Hospital, (50), 48–55. Retrieved from https://jcmhch.com.vn/index.php/home/article/view/1401