Abstract
Background: Primary synovial sarcoma of lung is an extremely rare tumor. The etiology and pathogenesis of sarcomas lung are not well understood. A definitive diagnosis requires detailed connecting clinical symptoms, radiological imaging, immunohistochemical staining and may be molecular genetics techniques.
Case Report: A male patient, 46 years old, history disease about 5 days with dry cough, dyspnea and right chest pain. Image manifestations: right pleural effusion and lung collapse. He had been taken the right pleural drainage and then the right lung surgery to remove the tumor. Right lung tumors are associated with right pleura, pericardium and mediastinal invasions. The diagnosis is confirmed with immunohistochemical staining of positive specific markers: PanCK, CD 5/6, CD99, Bcl-2, Calretinin, WT-1, Podoplanin
Conclusions: Primary Pulmonary Synovial Sarcom is a mesenchymal malignant disease in the lungs, very rare. The disease progresses rapidly, involving the parenchyma of the lungs, pleura, or pericardium, the lymph nodes or nearby tissues. The diagnosis have determined by immunohistochemistry.
References
A. Bhagya Lakshmi, K. Satya Sri, B. V. S. Kartheek, Nagarjun Rao; Primary monophasic synovial sarcoma, a rare pulmonary mesenchymal neoplasm: report of a case with review of literature; Int J Res Med Sci. May 2015;3(5): pp 1269-1271.
Arun RD; A Rare Primary Synovial Sarcoma of Lung - Case Report with Literature Review; J Nurs Health Sci, Volume 3, Issue 1, March, 2017, pp 15-22.
Devrim Cabuk, Berna Ustuner, Asli Gul Akgul, Ozgur Acikgoz, Busra Yaprak, Kazim Uygun, Salih Topcu, Bahar Muezzinoglu; Primary Synovial Sarcoma of Lung; Korean J Thorac Cardiovasc Surg 2014;47: pp 306-309.
Hartel PH and Parker JE; Unusual histology in primary pulmonary synovial sarcoma: Pearls to avoid misdiagnosis; Medical Case Reports and Reviews, 2018, Volume 1(1): pp 1-4.
Nagarjun Rao & Cesar A. Moran; Synovial Sarcoma, In: Pulmonary Pathology, Series Editor: Saul Suster - Demos Surgical Pathology, 2014, pp 140-141.
Richard A Rison; A guide to writing case reports for the Journal of Medical Case Reports and BioMed Central Research Notes; Journal of Medical Case Reports 2013, 7: pp 239.
Rosalia de Necochea-Campion, Lee M. Zuckerman, Hamid R. Mirshahidi, Shahrzad Khosrowpour, Chien-Shing Chen and Saied Mirshahidi; Metastatic biomarkers in synovial sarcoma; Biomarker Research (2017) 5:4, pp 1-8.
S. Dacic, T.J. Franks and M. Ladanyi; Synovial Sarcoma, In: WHO Classification of Tumours of The Lung, Pleura, Thymus and Heart, International Agency For Research on Cancer, Lyon, 2015, Fourth Edition, pp 127-131.
Shery Dennison, Eric Weppler, George Jaccopee; Primary Pulmonary Synovial Sarcoma: A Case Report and Review the Current Diagnostic and Therapeutics Standards; The Oncologist 2014;9, pp 339-342.
Timothy C. Allen, Phlip T. Cagle & Douglas B. Flieder; Mesenchymal and Miscellaneous Neoplasms, In: Spencer’s Pathology of The Lung, Phlip Hasleton & Douglas B. Flieder, Sixth Edition, 2013, Volume 2, pp 1281-1283.
Wang Rong Li, Chandan Thakur and Sohan Gupta; Primary Pulmonary Synovial Sarcoma: One Case Report; Journal of Lung Cancer Diagnosis & Treatment, 2017, 2:2, pp 114-125.
| Published | 20-02-2020 | |
| Fulltext |
|
|
| Language |
|
|
| Issue | No. 59 (2020) | |
| Section | Case report | |
| DOI | 10.38103/jcmhch.2020.59.15 | |
| Keywords | Sarcom hoạt dịch nguyên phát ở phổi; Hóa mô miễn dịch; Kết hợp gen SYT-SSX. Primary Pulmonary Synovial Sarcoma; Immunohistochemistry; SSX SYT-SSX Fusion Gene. |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2020 Journal of Clinical Medicine Hue Central Hospital