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Abstract
Granular cell tumors (GCTs) are rare, typically benign, solitary neoplasms that can manifest throughout the body, with reported cases in the tongue, esophagus, colon, skin, vulva, and musculoskeletal system. While GCTs are often asymptomatic, esophageal GCTs can grow large enough to cause dysphagia. In patients presenting with dysphagia, a broad differential diagnosis is necessary, encompassing common etiologies such as esophageal strictures, eosinophilic esophagitis, carcinoma, esophageal webs and rings, achalasia, and motility disorders. However, GCTs may not be readily considered. Due to their rarity, this case report aims to increase awareness of esophageal GCTs and highlight the key steps in diagnosing and managing this uncommon but treatable cause of dysphagia. The case details the clinical course of a patient with chief complaint of dysphagia, found to have a subepithelial esophageal tumor on upper gastrointestinal endoscopy (EGD) and endoscopic ultrasound (EUS). Histopathological examination in conjunction with immunohistochemical staining of the tissue biopsy confirmed the etiology of the symptomatic esophageal mass as a GCT. The patient’s dysphagia resolved following endoscopic mucosal resection of the GCT, and follow-up evaluations remain negative for recurrence. This case emphasizes esophageal GCT as an infrequent source of dysphagia and the need for EGD and EUS evaluation of subepithelial esophageal lesions with histopathological analysis for definitive diagnosis of GCT
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| Published | 07-11-2024 | |
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| Issue | Vol. 16 No. 7 (2024) | |
| Section | Case report | |
| DOI | 10.38103/jcmhch.16.7.15 | |
| Keywords | Báo cáo ca bệnh, mô bệnh học, khó nuốt, thực quản, u tế bào hạt Case report, histopathology, dysphagia, esophagus, granular cell tumor |
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