Tải xuống
Tóm tắt
Aims: To assess the prevalence and general characteristics of obstructive sleep apnea syndrome in patients with hypertension, investigate the relationship between obstructive sleep apnea syndrome and blood pressure, and the effectiveness of continuous positive pressure ventilation treatment after 1 month in hypertensive patients with obstructive sleep apnea.
Methods: Cross-sectional descriptive study with follow-up after 1 month in hypertensive patients treated at the Hue University of Medicine and Pharmacy Hospital with respiratory polygraphy from January 2021 to June 2023. Patients were given history, clinical examination, anthropometric measurements, Lipid profile test, intravenous glucose, Epworth scale assessment, CPAP treatment and re-evaluated after 1 month.
Results: 134 patients were registered for the study from 01/2021 to 06/2023. Hypertensive patients with OSAS were 73.13%. BMI in the OSAS (+) group was 22.84 ± 3.04 kg/m2 and was statistically significantly greater than the OSAS (-) group: 22.79 ± 3.07 kg/m2 (p<0.05). Neck circumference in the OSAS (+) group was 37.45 ± 2.44 cm, which was statistically significantly larger than the OSAS (-) group: 36.36 ± 1.57 cm (p<0.05). The rate of loud snoring during sleep and excessive daytime sleepiness in the OSAS patient group was statistically significantly higher than in the group without this syndrome (p<0.05 and p<0.01). The average systolic blood pressure in the OSAS (+) group was 154.79 ± 13.32 mm Hg and was statistically significantly higher than the OSAS (-) group (p<0.01). AHI has a moderate positive correlation with systolic blood pressure (r = 0.45, p<0.01) and diastolic blood pressure (r = 0.34, p<0.01). CPAP treatment improved systolic and diastolic blood pressure and symptoms of excessive daytime sleepiness.
Conclusion: There is a relationship between obstructive sleep apnea syndrome and hypertension. CPAP treatment improves blood pressure and daytime sleepiness.3
Tài liệu tham khảo
Ip MS, Lam B, Lauder IJ, Tsang KW, Chung K-f, Mok Y-w, et al. A community study of sleep-disordered breathing in middle-aged Chinese men in Hong Kong. 2001;119(1):62-9.
Mirrakhimov AE, Sooronbaev T, Mirrakhimov EM. Prevalence of obstructive sleep apnea in Asian adults: a systematic review of the literature. 2013;13:1-10.
Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). European Heart Journal. 2018;39(33):3021-104.
McEvoy RD, Antic NA, Heeley E, Luo Y, Ou Q, Zhang X, et al. CPAP for prevention of cardiovascular events in obstructive sleep apnea. 2016;375(10):919-31.
American Academy of Sleep Medicine Task Force. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. 1999;22(5):667.
Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, et al. 2020 International Society of Hypertension global hypertension practice guidelines. 2020;75(6):1334-57.
Inoue S, Zimmet P, Caterson I, Chunming C, Ikeda Y, Khalid A, et al. The Asia-Pacific perspective: redefining obesity and its treatment. 2000. doi: 10.4082/kjfm.2016.37.6.309
Xia W, Jing Y, Yuan C. Correlation between Obstructive Sleep Apnea Syndrome (OSAS) and Cognitive Dysfunction in Elderly Patients with Hypertension. 2023;22(4).
Hamdan AAM, Babiker AB, Alhag OAM, Ahmed KAHM. The Impact of Continuous Positive Airway Pressure on Controlling Hypertension in Patients Diagnosed with Obstructive Sleep Apnea: An Observational Prospective Cohort study. 2023.
Punjabi NM. The epidemiology of adult obstructive sleep apnea. 2008;5(2):136-43.
Lipford MC. Book Review: Principles and Practice of Sleep Medicine. LWW; 2017.
Ahbab S, Ataoğlu HE, Tuna M, Karasulu L, Çetin F, Temiz LÜ, et al. Neck circumference, metabolic syndrome and obstructive sleep apnea syndrome; evaluation of possible linkage. 2013;19:111.
Al-Jewair TS, Nazir MA, Al-Masoud NN, Alqahtani ND. Prevalence and risks of habitual snoring and obstructive sleep apnea symptoms in adult dental patients. 2016;37(2):183.
Huang Z, Aarab G, Chattrattrai T, Su N, Volgenant CM, Hilgevoord AA, et al. Associated factors of primary snoring and obstructive sleep apnoea in patients with sleep bruxism: A questionnaire study. 2022;49(10):970-9.
Lal C, Weaver TE, Bae CJ, Strohl KP. Excessive daytime sleepiness in obstructive sleep apnea. Mechanisms and clinical management. 2021;18(5):757-68.
Asha’ari ZA, Hasmoni MH, Ab Rahman J, Yusof RA, Lope Ahmad RA. The association between sleep apnea and young adults with hypertension. 2012;122(10):2337-42.
Monahan K, Redline S. Role of obstructive sleep apnea in cardiovascular disease. 2011;26(6):541.
Labarca G, Schmidt A, Dreyse J, Jorquera J, Enos D, Torres G, et al. Efficacy of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH): Systematic review and meta-analysis. 2021;58:101446.
Chen Q, Cheng Y-B, Shen M, Yin B, Yi H-H, Feng J, et al. A randomized controlled trial on ambulatory blood pressure lowering effect of CPAP in patients with obstructive sleep apnea and nocturnal hypertension. 2020;29(1):21-30.
Venkatnarayan K, Devaraj U, Veluthat C, Louis V, Ramachandran P, D’Souza G, et al. The effect of CPAP therapy on excessive daytime sleepiness and quality of life in subjects with obstructive sleep apnoea: an AB design study. 2021;25:1351-7.
Bonsignore MR, Pepin JL, Cibella F, Barbera CD, Marrone O, Verbraecken J, et al. Excessive daytime sleepiness in obstructive sleep apnea patients treated with continuous positive airway pressure: data from the European sleep apnea database. 2021;12:690008.
| Đã xuất bản | 28-12-2024 | |
| Toàn văn |
|
|
| Ngôn ngữ |
|
|
| Số tạp chí | Số 95 (2024) | |
| Phân mục | Nghiên cứu | |
| DOI | 10.38103/jcmhch.95.8 | |
| Từ khóa | Hypertension, respiratory polygraphy, Obstructive sleep apnea syndrome, OSAS |
công trình này được cấp phép theo Creative Commons Attribution-phi thương mại-NoDerivatives 4.0 License International .
Bản quyền (c) 2024 Tạp chí Y học lâm sàng Bệnh viện Trung Ương Huế