Regimens of EM/CO in treatment of hish-risk gestational trophoblastic neoplasms

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Objectves:

1) To study signs and symptom of high risk gestational trophoblastic neoplasms

2) Role of multi-agents chemotherapy in treatment of high-risk patients.

Methods: A perspective study.

Materials: 25 patients who had high-risk gestational trophoblastic neoplasms were treated in department of Obstetrics and Gynecology, Hue Central Hospital.

Results: Mean age of patients was 28.3±7.5, risk-score was 8.6±0.8, number of cycles of chemotherapy was 8.3±3.4, rate of success of the regimen was 96%, only 28% of patients had total hysterectomy, 100% of patients had side-effects, of that the most common was hair-loss. 12 pateints were pregnant after treatment, 41.7% of them reached term pregnancy.

Conclusion: Multi-agents chemotherapy with EM/CO regimen is safe and effective in treatment of high- risk gestaional trophoblastic neopalsia.

Tài liệu tham khảo

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Đã xuất bản 19-08-2016
Toàn văn
pdf (English)     11    3
Ngôn ngữ
Số tạp chí Số 36 (2016)
Phân mục Nghiên cứu
DOI
Từ khóa High-risk gestational trophoblastic neoplasms, EM/CO, pregnancy

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Hoang, B. N., Le, S. P., Dinh, T. P. M., Hoang, L. N., Le, T. Y. N., & Hoang, T. H. (2016). Regimens of EM/CO in treatment of hish-risk gestational trophoblastic neoplasms. Tạp Chí Y học lâm sàng Bệnh viện Trung Ương Huế, (36), 46–51. Truy vấn từ https://jcmhch.com.vn/index.php/home/article/view/1687