Treatment of kaposiform hemangioendothelioma with kasabach-merritt syndrome by corticosteroids and vincristine

Tải xuống

Dữ liệu tải xuống chưa có sẵn.
pdf     62    12

Tóm tắt

Objectives: To evaluate the results of corticosteroids and vincristine in the management of Kaposiformhemangioendothelioma(KHE) with Kasabach-Merritt syndrome.

Materials and Methods: Case series review.

Results: Six cases had KHE with Kasabach-Merritt syndrome and were treated by corticosteroids in combination with vincristine. The complete response, partial response and no apparent response were achieved at 50%, 33.3% and 16.7% among the study group respectively. Vincristine had mild and transient side effects compared to corticosteroids.

Conclusion: Corticosteroids and vincristine may be first-line therapy in the management of KHE with Kasabach-Merritt syndrome.

Tài liệu tham khảo

O’Rafferty C, O’Regan GM, Irvine AD, Smith OP. Recent advances in the pathobiology and management of Kasabach-Merritt phenomenon. British Journal of Haematology 2015; 171(1): 38-51.

Wang Z, Li K, Yao W, Dong K, Xiao X, Zheng S. Steroid-resistant kaposiform hemangioendothelioma: a retrospective study of 37 patients treated with vincristine and long-term follow-up. Pediatric Blood & Cancer 2015; 62(4): 577-80.

Haisley-Royster C, Enjolras O, Frieden IJ, et al. Kasabach-Merritt phenomenon: a retrospective study of treatment with vincristine. Journal of Pediatric Hematology/Oncology 2002; 24(6): 459-62.

Nguyễn Quang Anh, Nguyễn Quốc Hải, Lê Thanh Tùng. Hội chứng Kasabach-Merritt: chẩn đoán, điều trị qua 10 trường hợp tại Bệnh viện Nhi Đồng 2 từ 2001-2011. Y học TP. HCM 2011; 15(3): 160-3.

Drucker AM, Pope E, Mahant S, Weinstein M. Vincristine and corticosteroids as first-line treatment of Kasabach-Merritt syndrome in kaposiform hemangioendothelioma. Journal of Cutaneous Medicine and Surgery 2009; 13(3): 155-9.

Tlougan BE, Lee MT, Drolet BA, Frieden IJ, Adams DM, Garzon MC. Medical management of tumors associated with Kasabach-Merritt phenomenon: an expert survey. Journal of Pediatric Hematology/Oncology 2013; 35(8): 618-22.

Fahrtrash F, McCahon E, Arbuckle S. Successful treatment of kaposiform hemangioendothelioma and tufted angioma with vincristine. Journal of Pediatric Hematology/Oncology 2010; 32(6): 506-10.

Liu X, Li J, Qu X, et al. Clinical outcomes for systemic corticosteroids versus vincristine in treating kaposiform hemangioendothelioma and tufted angioma. Medicine 2016; 95(20): e3431.

Garcia-Monaco R, Giachetti A, Peralta O, et al. Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon: successful treatment with embolization and vincristine in two newborns. Journal of Vascular and Interventional Radiology (JVIR) 2012; 23(3): 417-22.

Đã xuất bản 19-08-2016
Toàn văn
pdf     62    12
Ngôn ngữ
Số tạp chí Số 36 (2016)
Phân mục Nghiên cứu
DOI
Từ khóa Kaposiformhemangioendothelioma, Kasabach-Merritt syndrome, vincristine Kaposiformhemangioendothelioma, Kasabach-Merritt syndrome, vincristine

Creative Commons License

công trình này được cấp phép theo Creative Commons Attribution-phi thương mại-NoDerivatives 4.0 License International .

Bản quyền (c) 2025 Tạp chí Y học lâm sàng Bệnh viện Trung Ương Huế

Nguyen, M. T., Phan, N. L. A., Tran, N. K. A., & Cao, T. T. C. (2016). Treatment of kaposiform hemangioendothelioma with kasabach-merritt syndrome by corticosteroids and vincristine. Tạp Chí Y học lâm sàng Bệnh viện Trung Ương Huế, (36), 25–29. Truy vấn từ https://jcmhch.com.vn/index.php/home/article/view/1632